132131-24-9
- Product Name：2-Amino-5-iodobenzonitrile
- Molecular Formula：C7H5IN2
- Purity：99%
- Molecular Weight：244.035
Product Details;
CasNo： 132131-24-9
Molecular Formula： C7H5IN2
Reputable factory supply 2-Amino-5-iodobenzonitrile 132131-24-9 in stock with high standard
- Molecular Formula:C7H5IN2
- Molecular Weight:244.035
- Melting Point:86℃ (ethanol )
- Boiling Point:333.622 °C at 760 mmHg
- PKA:1.02±0.10(Predicted)
- Flash Point:155.569 °C
- PSA：49.81000
- Density:1.981 g/cm3
- LogP:2.32628
132131-24-9 Relevant articles
Synthesis of 7-[123I]idotacrine: A potential SPECT agent to map acetylcholinesterase
Akula, Murthy R.,Kabalka, George W.
, p. 959 - 964 (1999)
9-Amino-1,2,3,4-tetrahydroacridine (Tacr...
Synthesis and in vitro biological evaluation of novel quinazoline derivatives
Zhang, Yaling,Zhang, Ying,Liu, Juan,Chen, Li,Zhao, Lijun,Li, Baolin,Wang, Wei
, p. 1584 - 1587 (2017)
A series of novel 4-arylamino-6-(5-subst...
2-Cyano-4-iodo-acetanilide: A hydrogen-bonded chain of R 2 2(12) and R22(14) rings
Garden, Simon J.,Custodio, Cintia De A.,Wardell, James L.,Low, John N.,Glidewell, Christopher
, p. o408-o410 (2007)
The mol-ecules of 2-cyano-4-iodo-acetani...
A novel DMSO-assisted regioselective iodination of aniline analogues
Bovonsombat, Pakorn,Lorpaiboon, Wanutcha,Laoboonchai, Sarocha,Sriprachaya-anunt, Prima,Yimkosol, Warangkana,Siriphatcharachaikul, Natthapatch,Siricharoensang, Pornpawit,Kangwannarakul, Terawee,Maeda, Jin,Losuwanakul, Satreerat,Mahesh Abhyankar, Maitraye
, (2020/10/05)
A metal- and oxidant-free electrophilic ...
Novel 4-arylaminoquinazolines bearing N,N-diethyl(aminoethyl)amino moiety with antitumour activity as EGFRwt-TK inhibitor
Zhang, Yaling,Chen, Li,Li, Xiabing,Gao, Li,Hao, Yunxia,Li, Baolin,Yan, Yaping
, p. 1668 - 1677 (2019/10/14)
Herein, four novel 4-arylaminoquinazolin...
Quinazoline-1-deoxynojirimycin hybrids as high active dual inhibitors of EGFR and α-glucosidase
Zhang, Yaling,Gao, Hongliang,Liu, Renjie,Liu, Juan,Chen, Li,Li, Xiabing,Zhao, Lijun,Wang, Wei,Li, Baolin
, p. 4309 - 4313 (2017/09/12)
A series of novel quinazoline-1-deoxynoj...
132131-24-9 Process route
-
-
1885-29-6
anthranilic acid nitrile
-
-
132131-24-9
5-iodoanthranilonitrile
| Conditions | Yield |
|---|---|
|
With
K(ICl2);
In
methanol; water;
at 20 ℃;
for 2h;
|
93% |
|
With
ammonium iodide; dihydrogen peroxide; acetic acid;
at 20 ℃;
for 12h;
|
92.6% |
|
With
ammonium iodide; dihydrogen peroxide; acetic acid;
at 20 ℃;
for 12h;
|
92.6% |
|
anthranilic acid nitrile;
With
ammonium iodide; acetic acid;
at 20 ℃;
for 0.5h;
With
dihydrogen peroxide;
In
water;
at 20 ℃;
for 12h;
|
92.6% |
|
With
Iodine monochloride; acetic acid;
at 20 ℃;
for 5h;
|
88% |
|
With
Iodine monochloride; acetic acid;
at 20 ℃;
for 3h;
|
84.9% |
|
With
hydrogenchloride; Iodine monochloride;
In
water;
at 20 ℃;
|
81% |
|
With
iodine;
In
tert-butyl methyl ether; dimethyl sulfoxide;
at 20 ℃;
for 7h;
Solvent;
regioselective reaction;
|
80% |
|
With
Iodine monochloride;
In
acetic acid;
for 3h;
Ambient temperature;
|
68% |
|
With
Iodine monochloride;
In
acetic acid;
at 20 ℃;
for 3h;
|
64% |
|
With
ammonium iodide; dihydrogen peroxide; acetic acid;
In
water;
at 20 ℃;
for 12h;
|
48% |
|
With
Iodine monochloride;
In
water;
|
45% |
|
With
Iodine monochloride;
|
|
|
With
ammonium iodide; dihydrogen peroxide;
In
acetic acid;
at 20 ℃;
for 24h;
|
|
|
With
Iodine monochloride; acetic acid;
at 25 - 35 ℃;
|
|
|
With
Iodine monochloride; acetic acid;
at 25 - 35 ℃;
for 3h;
|
-
-
516-12-1
N-iodo-succinimide
-
-
1885-29-6
anthranilic acid nitrile
-
-
132131-24-9
5-iodoanthranilonitrile
| Conditions | Yield |
|---|---|
|
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 18h;
|
73% |
132131-24-9 Upstream products
-
1885-29-6
anthranilic acid nitrile
-
878133-06-3
N-(2,4-diiodo-phenyl)-2,2,2-trifluoro-acetamide
-
533-70-0
2,4-diiodoaniline
-
540-37-4
p-aminoiodobenzene
132131-24-9 Downstream products
-
351425-99-5
2-(2-amino-5-iodophenyl)-4,5-dihydro-1H-imidazole
-
66682-68-6
2-amino-5-benzylbenzonitrile
-
378791-59-4
2-amino-5-(4'-fluorobenzyl)benzonitrile
-
378791-61-8
2-amino-5-(3'-methoxybenzyl)benzonitrile
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